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Future considerations of CTS include use of linked national registries to understand risk factors, explore possible screening methods, and evaluate diagnosis and treatment with a broader perspective beyond surgery, including psychological well-being

This sophisticated crosstalk, where parallel pro-apoptotic pathways (ATF4-driven induction and CHOP-mediated fine-tuning) converge on the CHAC1 promoter, allows for precise control of cell fate under prolonged ER stress (Nomura et al., 2020)

Is resection of colorectal liver metastases after a second-line chemotherapy regimen justified

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